| tel. | +41 76 3201066 |
| pkucera@unil.ch, kucera@fbmi.cvut.cz | |
| Cell, organ and systems physiology, photomedicine |
Personal
Current institution
Visiting professor, Faculty of Biomedical Engineering, Kladno, Czech Technical University.
Visiting professor, Ecole Polytechnique Fédérale de Lausanne, Switzerland.
Honorary professor, Medical Faculty, University of Lausanne, Switzerland.
Cofounder and consultant of Motilis Medica SA, Switzerland
Education
Faculty of medicine, Charles University, Prague, Czech Republic.
Faculty of biology and medicine, University of Lausanne, Switzerland.
Research
Mainly fundamental but closely linked to pathophysiological and clinical problems.
Oriented to answer concrete questions concerning mechanisms, diagnosis and therapy
of some diseases in the domains of gastroenterology, urology, cardiology and neurology.
Examples: analysis of human gastrointestinal motility, properties of human normal and
tumoral urothelium, myocardium in face of anoxia-reoxygenation, intracerebral
dissemination of neurotropic viruses.
Methods:
Imaging of optical signals in living specimens, microspectrofluorometry,
microrespirometry, electrophysiology, cell and tissue cultures.
Illustrative publications
- Pilot study trialling a new ambulatory method for the clinical assessment of regional gastrointestinal transit using multiple electromagnetic capsules. Neurogastroenterology and Motility 26:1783-1791 (2014)
- Detection of bladder cancer by fluorescence cystoscopy: from bench to bedside - the hexvix story. Handbook of Photomedicine, ed. M.R. Hamblin, Ying-Ying Huang, Taylor & Francis 2013, pp.411-425.
- Magnetic pill tracking: a novel non-invasive tool for investigation of human digestive motility. Neurogastroenterology and motility 17:148-154 (2005)
- Comparison of aminolevulinic acid and hexylester aminolevulinate induced protoporphyrin IX distribution in human bladder cancer. J. Urology 170:428-432 (2003)
- Photodetection of early human bladder cancer based on the fluorescence of 5-amino-laevulinic acid hexylester-induced protoporphyrin IX: a pilot study. British Journal of Cancer 80:185-193 (1999)
- Pathways of the early propagation of virulent and avirulent rabies strains from the eye to the brain. J. Virology 55:158-162 (1985)